How does phenytoin cause gingival hyperplasia
WebApr 1, 2024 · In some patients (usually younger patients), tenderness, swelling, or bleeding of the gums (gingival hyperplasia) may appear soon after phenytoin treatment is started. … WebThis literature review confirms that long-term use of phenytoin causes gingival hyperplasia, as does the use of valproate, carbamazepine and phenobarbital. Patients taking carbamazepine or phenytoin had alveolar bone loss. However, the effects of newer-generation antiepileptic drugs on oral health have not yet been studied.
How does phenytoin cause gingival hyperplasia
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WebMay 19, 2011 · Pathogenesis of phenytoin-induced gingival overgrowth. Several mechanisms are involved in the development of gingival overgrowth. Phenytoin induces a … WebSeveral distinct classes of drugs, such as anticonvulsants, immunosuppressants, and calcium channel blockers, caused gingival overgrowth. One of the main drugs associated …
WebJun 2, 2024 · Gingival health has altered physiology in many conditions ranging from local to systemic linked causes. Gingival enlargement or hyperplasia is not an uncommon oral health issue as it is usually symptomatic with bleeding, bad breath, and an unsightly puffed or inflamed appearance. Read the article to find out the causes, types, and management … WebSep 26, 2024 · anti-seizure drugs, such as phenytoin. immunosuppressants, such as cyclosporine and tacrolimus. calcium channel blockers, such as nifedipine and …
WebPhenytoin sodium is known to be the most common cause of gingival hyperplasia. 1,4 A minor degree of hyperplasia occurs quite commonly and this generally causes only … WebGingival hyperplasia was very common in patients taking PHT (16%-94% of patients). Alveolar bone loss occurred in patients taking carbamazepine or PHT. Patients taking valproate, carbamazepine or phenobarbital also had gingival hyperplasia. We found no published studies of newer-generation AEDs.
WebJan 6, 2024 · Gingival hyperplasia is often a painful condition that can cause the following: Red and/or bleeding gums Bad breath Plaque buildup on teeth Tender/inflamed gums Pain This condition also negatively impacts your oral health standing. If left untreated, your gums can begin to fully cover your teeth, causing poor oral hygiene.
WebPhenytoin can cause the platelet or white blood cell counts to drop, increasing the risk of bleeding or infection, respectively. Phenytoin also can cause anemia. ... Picture of Gingival Hyperplasia from Phenytoin. Gingival hyperplasia from phenytoin. Gingival hyperplasia can result in some patients who are taking the anti-seizure medication... line up tool for clutchline up traductionWebPhenytoin sodium is known to be the most common cause of gingival hyperplasia. 1,4 A minor degree of hyperplasia occurs quite commonly and this generally causes only cosmetic problems, especially for women. However, when phenytoin is used for prolonged periods in high dosage a severe degree of gingival overgrowth occurs. line up walesWebJun 7, 2024 · The differential diagnosis of gingival hyperplasia includes poor oral hygiene, medications like cyclosporine and phenytoin, systemic illnesses like sarcoidosis or Crohn’s disease, hematological disorders like AML, and genetic conditions. Patients can experience gingival hyperplasia because of leukemic infiltration into the gums. line up warner newsroomWebThe most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by … hot tub cover in stockWebWhich antiepileptic drug may cause gingival hyperplasia? Phenytoin Gabapentin Phenobarbital Levetiracetam Phenytoin The patient taking carbamazepine should be instructed to avoid taking the medication with which beverage? Grape juice Apple juice Orange juice Grapefruit juice Grapefruit juice The nurse is administering intravenous … line up vitality csgoWebSep 19, 2024 · Phenytoin (PHT, or 5,5-diphenylhydantoin), sodium valproate, phenobarbitone, vigabatrin, primidone, mephenytoin, and ethosuximide are some of the drugs that cause gingival hypertrophy. However, phenytoin is the anticonvulsant most associated with gingival enlargements. It is used to treat temporal lobe, tonic-clonic, and … line up wcd