Etoposide, sold under the brand name Vepesid among others, is a chemotherapy medication used for the treatments of a number of types of cancer including testicular cancer, lung cancer, lymphoma, leukemia, neuroblastoma, and ovarian cancer. It is also used for hemophagocytic lymphohistiocytosis. It is used by mouth or injection into a vein. WebEtoposide is a semisynthetic derivative of the podophyllotoxins, an epipodophyllotoxin. It inhibits DNA topoisomerase II, thereby inhibiting DNA synthesis. Etoposide is cell cycle dependent and phase specific, affecting mainly the S and G 2 phases. 1. PHARMACOKINETICS: Interpatient variability bioavailability
Etoposide Injection, USP - DailyMed
WebDESCRIPTION. Toposar ® (etoposide injection USP) (also commonly known as VP-16) is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases. It is 4'-demethylepipodophyllotoxin 9-[4,6-0-(R)-ethylidene-β-D-glucopyranoside]. It is very soluble in methanol and chloroform, slightly soluble in ethanol, and sparingly … WebHow to use Etoposide Vial. This medication is given by slow injection into a vein by a health care professional. It is given as directed by your doctor, usually over 30 to 60 minutes every day or ... ingredients magic mouthwash
DailyMed - ETOPOSIDE injection
WebEtoposide, therefore, is cleared by both renal and nonrenal processes, i.e., metabolism and biliary excretion. The effect of renal disease on plasma etoposide clearance is not … WebEtoposide is a type of chemotherapy. It is a treatment for a number of different types of cancer. Find out about how you have it, possible side effects and other important … WebFeb 28, 2024 · Methods. Patients received socazolimab (5 mg/kg) every three weeks until disease progression or physician decision. Carboplatin (area under the curve: 5) was also administered every three weeks and etoposide (100 mg/m 2) on days 1, 2, and 3 of the treatment cycle.The primary purpose of the study was safety measured by the Common … mixed inhibitors lineweaker burke