Cst smad3
WebSep 15, 2024 · Sequencings and proteomics revealed that YAP bound to Smad3 and promoted the proliferation of hBdSMC via MAPK/ERK signaling pathway in stiff ECM. Moreover, CUT and TAG sequencing and dual-luciferase assays demonstrated that Smad3 inhibited the transcription of JUN. The YAP inhibitor CA3 was used in a partial bladder … WebApr 10, 2024 · TGF-beta 506 transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 507 and ERK/Sp1 signaling pathways. ... at 4°C overnight. All antibodies are purchased from Cell Signaling 717 Technology (CST, Danvers, MA, USA), except the EGFR antibody cocktail (Cat 718 No. AHR5062, RRID: …
Cst smad3
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WebPhospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) (D27F4) Rabbit mAb (PE Conjugate) 11979S 美国Cell Signaling Technology(CST) 100μl TGF-beta/Smad Signaling Monoclonal Antibody 4C Phospho-BACH1/BRIP1 (Thr1133) Antibody 11983S 美国Cell Signaling Technology(CST) 100μl Cell Cycle / Checkpoint Polyclonal Antibody -20C WebPolyclonal Antibody for studying Smad3. Cited in 177 publications. Validated for WB, IP, IF. Highly specific and rigorously validated in …
WebAnti-phospho Smad1/Smad5/Smad8 (Ser463/465)-Antikörper from rabbit, purified by affinity chromatography; Synonyms: Mothers against decapentaplegic homolog 1, BSP-1, hSMAD1, JV4-1, MAD homolog 1, Mothers against DPP homolog 1, Mad-related protein 1, SMAD 1, SMAD family member 1, Smad1, Transforming growth factor-beta-signaling … WebNational Center for Biotechnology Information
Web本发明所述多肽,可以有效结合子宫内膜癌细胞中异常增多的突变型tp53,抑制smad3的磷 酸化 和子宫内膜癌生长,从而降低放疗剂量以及 化疗药物 的使用浓度,提高子宫内膜癌细胞的 放化疗 敏感性,且对正常细胞无明显 副作用 。 WebFeb 1, 2024 · Reciprocally, phosphorylation of SMAD3, the principal signal transducer of the TGFβ receptor, was up-regulated by over-expression of Gpr180 9. However, in the mouse liver phosphorylation of SMAD2 ...
WebApr 25, 2024 · TGF-β1 binds to its receptor to trigger intracellular signaling and phosphorylates Smad2 and Smad3. Phosphorylated Smad2 and Smad3 are transported to the nucleus and regulate the transcription of target genes . Consequently, blocking the EMT of alveolar epithelial cells (AECs) might be a promising strategy for the treatment of PF.
WebFeb 11, 2024 · 松果菊苷(上海融禾医药科技发展有限公司,纯度97%,批号:190906);兔多克隆抗体TGF-β1(美国 Abcam 公司);phospho-Smad2(p-Smad2,美国 CST 公司);phospho-Smad3(p-Smad3, Bioss公司);蛋白Marker(美国Thermo 公司);Trizol 试剂(加拿大Roche 公司);逆转录试剂盒(谷歌 ... tim montana tour datesWebJan 25, 2024 · A pan acetylation antibody (9441S, CST) was used. H) KAT6A knockdown (KD) decreases the acetylation (Ac-Lys) of SMAD3 in MDA-MB-231 cells. I) Effect of acetyltransferase activity-deficient mutants G657E and C543G/G657E of KAT6A on SMAD3 acetylation. J) MS analysis of acetylation sites of SMAD3 by KAT6A. ... In addition, in … parks preventive and social medicineWebAug 14, 2024 · Smad3 directly induces Smad7 production, while Smad7 contributes to the degradation of Smad3. 14 In this study, renal IRI significantly induced the upregulation of TGF-β1 at both mRNA and protein levels during the AKI-to-CKD continuum. The increase of TGF-β1 resulted in the upregulation of p-Smad2, p-Smad3, and Smad4, as well as the ... tim moody on facebookWebPhospho-Smad3 (Ser423/425) (C25A9) Rabbit mAb detects endogenous levels of Smad3 when phosphorylated at Ser423/425. This antibody does not cross-react with other family members. ... but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Antibody Performance Guarantee. tim moody maineWebGenetic locus: SMAD3 (human) mapping to 15q22.33; Smad3 (mouse) mapping to 9 C. SOURCE p-Smad3 (1D9) is a mouse monoclonal antibody raised against Ser 425 phosphorylated Smad3 of human origin. PRODUCT Each vial contains 100 µg IgG in 1.0 ml of PBS with < 0.1% sodium azide, 0.1% gelatin, 1% glycerol and < 0.1% stabilizer … tim moody naplesWebMonoclonal Antibody for studying Smad3. Cited in 555 publications. Validated for WB, IP, IF, F, ChIP, ChIP. Available in 2 sizes. Highly … tim moody obituaryWebMar 12, 2024 · A bleomycin-induced pulmonary fibrosis animal model used SD rats. Morphological changes were analyzed by hematoxylin-eosin staining. RT-qPCR and western blot were used for the detection of the expression of TGF-β1, collagen I, collagen III, E-cadherin, fibronectin and the ratios of p-Smad2/Smad2, p-Smad3/Smad3. timmons wood products