WebABCG2 is a translocation protein used to actively pump drugs and other compounds against their concentration gradient using the bonding and hydrolysis of ATP as the … Web2 days ago · More information: Rogier W Bentires-Alj, N-acetylcysteine overcomes NF1-loss-driven resistance to PI3K alpha inhibition in breast cancer, Cell Reports Medicine …
The analysis of doxorubicin resistance in human breast cancer …
WebMutations, and Overcoming Drug Resistance. Human epidermal growth factor receptor 2 (HER2), a receptor tyrosine kinase, is a major drug target and clinical biomarker in … WebJun 1, 2024 · Resistance mechanisms. Anti-Resistance strategy. 1. Introduction. The chemoresistance mainly embodied in the insensitive of cancer cells to therapy, which is a key factor result in the failure of anti-breast cancer chemotherapy. According to drug responsiveness, drug resistance can be classified into intrinsic resistance and acquired … didn\u0027t cha know youtube
Characterization of SN38-resistant T47D breast cancer cell …
WebApr 14, 2024 · Lapatinib-resistant breast cancer cells have higher levels of autophagic activity and they can be sensitized to treatment upon inhibition of autophagy ... Wang, Y.; Hu, G.R.; Wang, Q.; Shao, J.K. Expression of HMGB1 protein in breast cancer and its clinicopathological significance. Zhonghua Bing Li Xue Za Zhi 2024, 49, 57–61. [Google … WebOct 23, 2003 · The new transporter was termed the breast cancer resistance protein (BCRP), because of its identification in MCF-7 human breast carcinoma cells. BCRP is a 655 amino-acid polypeptide, formally ... WebApr 23, 2024 · Background. Although several novel resistant breast cancer cell lines have been established, only a few resistant breast cancer cell lines overexpress breast cancer resistance proteins (BCRP).The aim of this study was to establish new resistant breast cancer cell lines overexpressing BCRP using SN38 (7-ethyl-10-hydroxycamptothecin), … didnt pass the bar crossword clue