WebFeb 24, 2015 · The drug is given as a 0.75 mg/kg bolus followed by a 1.75 mg/kg/h infusion while the PCI is being performed. Patients treated with bivalirudin should have an ACT measured five minutes after the start of the infusion. If the ACT is <225 seconds, the patient should be given an additional 0.3 mg/kg bolus. The pharmacokinetics and … WebBackground Bivalirudin is an ultrashort acting direct thrombin inhibitor, which has been used in place of heparin in selected settings. We describe our preliminary experi-ence with the use of bivalirudin in patients who required anticoagulation for a deep vein thrombosis, prosthetic heart valve, or hypercoagulable state but were felt to be at high
Diagnosis and Management of Heparin-Induced …
WebJun 3, 2024 · IF ON warfarin AT TIME OF INITIATION: Reverse the warfarin using Vitamin K 5 mg PO X1 after argatroban has started; call Attending if patient is unable to take oral … WebAug 3, 2024 · Evaluation of dose requirements for prolonged bivalirudin administration in patients with renal insufficiency and suspected heparin-induced thrombocytopenia. J … rayleigh roughness criterion
A Review of Bivalirudin for Pediatric and Adult Mechanical
WebNov 18, 2024 · Periprocedural bridging management of anticoagulation. Circulation 2012; 126:486. Tafur A, Douketis J. Perioperative management of anticoagulant and antiplatelet therapy. Heart 2024; 104:1461. Kuo HC, Liu FL, Chen JT, et al. Thromboembolic and bleeding risk of periprocedural bridging anticoagulation: A systematic review and meta … WebNov 10, 2024 · The average rate of bivalirudin required to maintain pre-specified anticoagulation targets differed between the studies, varying from 0.028 to 0.1 mg/kg/h [4, 9]. In an additional retrospective study of 11 adult patients by Netley et al. [ 12 ], bivalirudin was initiated at a rate of 2.5 mcg/kg/min (0.15 mg/kg/h), and dose adjustment was guided ... WebAfter 3-5 days of co-therapy with warfarin, temporarily suspend the bivalirudin for 4 hours, then check the INR. If the INR is <2.0, restart the bivalirudin and consider warfarin … simple white chest of drawers for kids